HIV related studies include ARV resistance, as well as complications to HIV (eg. Oral candidiasis, peripheral neuropathy, etc); Skin infection studies include impetigo, secondarily infected traumatic lesions, secondarily infected dermatoses, etc.; Cardiovascular includes hypertension, and cardiac endpoint studies.; Influenza includes treatment and vaccine studies. We have a capable Vaccine team who have been able to recruit large numbers of subjects with excellent data quality.; Respiratory includes both Asthma and COPD. Our respiratory team make use of our own spirometer to maintain and continually update our growing respiratory database. Vaccine therapeutic areas include influenza, meningitis and infectious diseases. We have the capabilities to conduct both paediatric and adult vaccine studies.